CIPLA-DOXORUBICIN may have unintended or undesirable effects. One of the most serious, and potential life-threatening, side-effects associated with CIPLA-DOXORUBICIN therapy is low white blood cell counts. White blood cells are necessary to maintain a healthy immune system and to fight infections. You should immediately report to your doctor if you develop fever or chills, cough or hoarseness, lower back or flank pain, painful or difficult urination or a sore throat.
Other serious side-effects, which you should report to your doctor as a matter of urgency, include:
- Allergic reactions, presenting with swelling of the face, lips, or throat, skin rash or hives, and difficulty breathing. Severe allergic reactions may result in death if not treated promptly.
- Swelling of the feet or legs, or shortness of breath accompanied by an inability to lie down or coughing of pink-coloured sputum, as these symptoms may be indicative of heart failure.
- Palpitations, as this may indicate heart damage.
- Ulcers in the mouth.
- Any bleeding complications, including vomiting of blood or blood per rectum.
- Severe foul-smelling diarrhoea accompanied by stomach cramps and fever as this may indicate infection or inflammation of the large bowel.
- Fever and/or chills.
Other side-effects with CIPLA-DOXORUBICIN that you should report to your doctor as soon as possible include:
- Secondary infections.
- Low red blood cell counts (presenting with tiredness or shortness of breath) and low platelet counts (presenting with easy bruising, pinpoint red spots on the skin, or bleeding from the gums).
- High blood uric acid levels causing attacks of gout, which usually presents with severe pain, swelling and redness of a joint, such as those of the big toe or knee. This occurs most commonly during initial treatment of patients with leukaemia or lymphoma as a result of rapid cell breakdown that leads to elevated blood uric acid concentrations.
- Painful red eyes with formation of pus (yellow discharge) or any reduction in vision.
- Pain, swelling or red streaks at the injection site.
- Nausea and vomiting (which may be severe).
- Heartburn or regurgitation or pain with eating, as this may indicate inflammation of the lining of the oesophagus or stomach or a stomach ulcer.
- Diarrhoea.
- Suppression of testicular or ovarian function. This may interfere with the production of sperm in men and the menstrual cycle in women.
Other side-effects with CIPLA-DOXORUBICIN that you should report to your doctor if they continue or become bothersome include:
- Tearing of the eyes.
- Hot flushes.
- Stomach pain.
- Loss of appetite.
- Redness with inflammation and pain of skin previously exposed to radiation therapy (radiation recall reactions).
- Hives (urticaria) occurring on sun-exposed skin.
- Skin rash or darkening of the nails, palms or soles.
- Reddening of the skin covering fingers, toes, ears and other peripheral parts.
- Generally feeling unwell and tiredness.
Other side-effects with CIPLA-DOXORUBICIN include:
- Dehydration.
- Darkening of the membrane inside the mouth.
- Changes in liver enzyme levels.
- Hair loss.
- Red discolouration of urine for 1 to 2 days after administration.
- Severe drop in blood pressure.
Not all side-effects reported for this medicine are included in this leaflet. Should your general health worsen while taking CIPLA-DOXORUBICIN, please consult your doctor, pharmacist or other healthcare professional for advice. If you notice any side-effects not mentioned in this leaflet, please inform your doctor or pharmacist.
