Coryx Cough And Cold 5 ml/10 mg/30 mg/1,25 mg Solution

CORYX COUGH AND COLD belongs to a group of medicines called antitussives and expectorants which relieve coughing and assist in the secretion of phlegm from the airways. CORYX COUGH AND COLD is used to relieve coughing.

Do NOT take CORYX COUGH AND COLD if you:

• Are hypersensitive (allergic) to dextromethorphan hydrobromide, pseudoephedrine hydrochloride, triprolidine hydrochloride or any of the other ingredients of CORYX COUGH AND COLD (listed in section 6).
• Have heart disease or any disease of your blood vessels, especially those blood vessels supplying the heart with blood.
• Have high blood pressure (hypertension).
• Have been diagnosed with an enlarged prostate gland.
• Have been diagnosed with an overactive thyroid gland.
• Have bladder dysfunction.
• Have been diagnosed with narrow angle glaucoma (a condition characterised by raised pressure inside the eye that may lead to blindness).
• Have been diagnosed with a tumour (abnormal growth) of your adrenal gland known as a pheochromocytoma.
• Are taking medicines known as monoamine oxidase inhibitors (for depression) or have stopped such treatment within the last 2 weeks (see other medicines and CORYX COUGH AND COLD).
• Are taking ephedrine or other medicines known as sympathomimetic agents (increase blood pressure or heart rate) (see other medicines and CORYX COUGH AND COLD).
• Please discuss this with your treating doctor or pharmacist if you are unsure.
• Are pregnant or breast feeding your baby (see Pregnancy, breastfeeding and fertility).
• Have asthma and are suffering from an asthma attack.
• Have been diagnosed with severe lung disease compromising your lung function.

CORYX COUGH AND COLD should not be given to children younger than 2 years of age.

Warnings and precautions

Take special care with CORYX COUGH AND COLD. CORYX COUGH AND COLD may lead to drowsiness and impaired concentration, which may become worse if you combine it with alcohol or other medicines or substances that suppress the function of the brain. You should not drive, climb dangerous heights or operate machinery as impaired decision-making may lead to accidents.

If you suffer from heart disease, heart failure (or are at risk of developing heart failure), chest pain when you are active (angina) or are taking digoxin (for heart failure or abnormal heart rhythms), you should not take CORYX COUGH AND COLD without discussing it with your treating doctor.

Do not share medicines prescribed for you with any other person. Always take CORYX COUGH AND COLD exactly as described in this leaflet or as your doctor, pharmacist or nurse has told you. Check with your doctor, pharmacist or nurse if you are not sure.

The dosage in adults and children over 12 years is 10 mL (2 teaspoons) three times a day.

For children aged between 6 and 12 years the dosage is 5 mL (1 teaspoon) three times a day.

In children 2 to 5 years the dosage is 2,5 mL (half a teaspoon) three times a day. These dosages should not be exceeded. CORYX COUGH AND COLD should not be given to children younger than 2 years of age.

If you take more CORYX COUGH AND COLD than you should If you take more CORYX COUGH AND COLD than you should, you may experience drowsiness, weakness, incoordination, difficulty with passing urine, irritability, high blood pressure, palpitations, stomach upset or struggle to breathe or develop convulsions (epileptic fits). Overdosage may result in death, especially in children and infants. Following overdosage children usually become stimulated or excited and may experience lack of coordination of muscle movements, see or hear things that are not real, experience muscle tremor, convulsions, or develop dilated pupils, dry mouth, flushed face and fever. Paranoid psychoses, delusions and hallucinations (seeing things that are not present) may also occur following an overdose of Pseudoephedrine which is contained in CORYX COUGH AND COLD.

In the event of overdosage, consult your doctor or pharmacist. If neither is available, contact the nearest hospital or poison control centre.

If you forget to take CORYX COUGH AND COLD If you miss a dose, take it as soon as you remember, and then continue as before. However, if it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed dose.

CORYX COUGH AND COLD can have side effects. Not all side effects reported for CORYX COUGH AND COLD are included in this leaflet. Should your general health worsen or if you experience any untoward effects while taking CORYX COUGH AND COLD, please consult your health care provider for advice.

If any of the following happens, stop taking CORYX COUGH AND COLD and tell your doctor immediately or go to the casualty department at your nearest hospital:

• Swelling of the hands, feet, ankles, face, lips and mouth or throat, which may cause difficulty in swallowing or breathing.
• Rash or itching.
• Fainting.
• Fever, coughing, sneezing, sore throat, skin ulcers and other signs of infection, as this may be due to low white cell counts.
• Pallor (paleness) accompanied by tiredness, shortness of breath, and chest pain, as this may indicate low red blood cell counts.
• Pinpoint red spots on the skin, easy bruising or bleeding from the gums, as this may be due to low platelet counts.
• Convulsions or epileptic fits.
• Confusion or any alteration in mental status.
• Loss of consciousness or loss of function of one side of the face or body or inability to move an arm or a leg.
• Chest pain.
• Extreme restlessness, involuntary movements and/or uncontrollable speech.
• Tightness of the chest or shortness of breath.
• Inability to pass urine.
• Hearing or seeing things which are not real. These are all very serious side effects. If you have them, you may have had a serious reaction to CORYX COUGH AND COLD. You may need urgent medical attention or hospitilisation.
• Reduction of physical movements.
• Muscle weakness.
• Pins and needles as this may indicate nerve damage.
• Blurred vision.
• Ringing in the ears.
• Thickened airway secretions.
• Any skin rash, including a rash that is worse on areas exposed to the sun.
• Difficulty to pass urine or pain with urination.
• Excessive thirst, excessive hunger and frequent urination, as this may indicate high blood glucose (sugar) levels.
• Impaired blood flow to the extremities (Hands and feet). These are all serious side effects. You may need urgent medical attention.
• Sweating.
• Sedation varying from slight drowsiness to deep sleep and including lassitude (lack of energy or listlessness), dizziness or incoordination.
• Sleeplessness, nervousness, rapid heart rate, tremors, or muscle twitching.
• Inability to concentrate, elation or depression, irritability, nightmares or other sleep disturbances, anxiety, restlessness, giddiness, or fear.
• Adverse mental effects (Especially in children).
• Headache.
• Tingling, heaviness and weakness of the hands.
• Palpitations.
• Dryness of the mouth, constipation, or heartburn.
• Nausea, vomiting, runny stomach, stomach cramps, stomach pain or loss of appetite.
• Hair loss.
• Muscle pain.
• Thirst.
• Flushing or pallor.
• Low blood pressure.
• Abnormal heart rhythms as well as slow or rapid heart rates.
• Constriction of the pupil.
• Ischaemic colitis (Inflammation of the large intestine).

If you notice any side effects not mentioned in this leaflet, please inform your doctor or pharmacist.

Reporting of side effects

If you get side effects, talk to your doctor, pharmacist or nurse. You can also report side effects to SAHPRA via the “6.04 Adverse Drug Reaction Reporting Form”, found online under SAHPRA’s publications: https://www.sahpra.org.za/Publications/Index/8. By reporting side effects, you can help provide more information on the safety of CORYX COUGH AND COLD.

Store all medicines out of reach of children. Store at or below 25 ºC. Protect from light. Do not use after the expiry date stated on the packaging material.

Return all unused medicine to your pharmacist. Do not dispose of unused medicine in drains or sewerage systems, for example toilets.