Lizorp 250 mg/500 mg Tablets

LIZORP is a broad spectrum cephalosporin antibiotic that is used to treat the following mild to moderately severe infections:

• Upper respiratory tract infections – tonsilitis and pharyngitis.
• Middle ear infection (otitis media).
• Sinusitis.
• Lower respiratory tract infections - bronchitis.
• Uncomplicated skin and skin structure infections.
• Uncomplicated urinary tract infections.

Do not take LIZORP :

• If you are allergic to cefprozil, cephalosporin antibiotics, other beta-lactam group of antibiotics or any of the other ingredients of LIZORP.
• Children that are younger than 1 year old.
• If you are pregnant or breastfeeding.

Take special care with LIZORP :

• Before you start taking LIZORP, tell your doctor if have had any allergic reactions to LIZORP, other cephalosporin antibiotics, penicillins, or other medicine. If you are allergic to penicillin, you should exercise extra caution as cross-sensitivity with LIZORP has been noted.
• Stop taking LIZORP immediately if you develop an allergic reaction (difficult breathing and/or swelling of lips, face and throat) and seek emergency medical help.
• LIZORP may cause pseudomembranous colitis. Contact your doctor if you have any of these symptoms - abdominal cramps, bloody stools, diarrhoea and/or fever.
• Tell your doctor if you have or had kidney disease in the past as your dosage of LIZORP may have to be adjusted.
• If you take LIZORP for a prolonged period, you may develop a superinfection meaning that a new infection can result that is resistant to LIZORP. Consult your doctor if you experience fever or chills, lower back or side pain, painful or difficult urination.
• Tell your doctor if you are taking water pills. Taking water pills together with LIZORP may affect kidney function.

Taking LIZORP with food and drink: LIZORP is not affected by food, and tablets may be taken before, during or after meals.

Pregnancy and breastfeeding: Safety of use in pregnancy and breastfeeding has not been established. If you are pregnant or breastfeeding your baby while taking LIZORP, please consult your doctor, pharmacist or other healthcare professional for advice.

Driving and Using Machinery: LIZORP may cause dizziness. If you feel dizzy while taking LIZORP do not drive and do not use hazardous tools or machines.

LIZORP contains lactose. If you have hereditary problems of galactose intolerance, the lapp lactase deficiency or glucose-galactose malabsorption, you should not take LIZORP.

Taking other medicines with LIZORP: Tell your doctor if you are taking any of the following medication:

• Other cephalosporin antibiotics - Taking LIZORP with other cephalosporin antibiotics may cause a decrease in your Vitamin K production which can affect blood clotting. Your doctor may advise you to take additional Vitamin K supplements especially if you are malnourished or seriously ill.
• Aminoglycoside antibiotics - taking LIZORP with aminoglycoside antibiotics can lead to kidney damage.
• Potent diuretics/ water tablets - taking LIZORP with diuretics may affect kidney function.

If you are taking other medicines on a regular basis, including complementary or traditional medicines, the use of LIZORP tablets with these medicines may cause undesirable interactions. Please consult your doctor, pharmacist or other healthcare professional, for advice.

Always take LIZORP exactly as your doctor has instructed you. You should check with your doctor or pharmacist if you are unsure. If you have the impression that the effect of LIZORP is too strong or too weak, talk to your doctor or pharmacist. Your doctor will prescribe an appropriate dose for you according to your condition.

If you take more LIZORP than you should:

• Symptoms of overdose may include: seizures, severe abdominal cramps and vomiting. In the event of overdosage, consult your doctor or pharmacist. If neither is available, seek help at the nearest hospital or poison centre.

If you forget to take LIZORP:

If you forget to take a dose of your medicine, take it as soon as you remember, and then continue as before. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

LIZORP can have side-effects. If any of the following happens, stop taking LIZORP and tell your doctor immediately to go to the casualty department of your nearest hospital:

• Anaphylaxis characterised by: Skin rash, hives, difficulty breathing, swelling of your face, lips, tongue, or throat and/or shock. These are all very serious side effects. If you have them, you have had a serious allergic reaction to LIZORP. You may need urgent medical attention or hospitalization.

Tell your doctor immediately or go to casualty department at your nearest hospital if you notice any of the following:

• black, tarry stools, chills, fever, cough, shortness of breath, unusual tiredness and weakness.
• Pseudomembranous colitis (abdominal cramps, watery, severe diarrhoea, fever).
• blistering, peeling, loosening of skin and mucous membranes, which may involve the eyes or other organ systems.
• chest pain, chills, fever, unusual bleeding and bruising.
• hives or wells, itching and redness of skin.
• Serum sickness (fever, joint pain, skin rash).
• abdominal or stomach pain, clay-coloured stools, dark urine, headache, loss of appetite, unpleasant smelling of breath.
• Superinfection (fever, hoarseness or cough, lower back or side pain, painful or difficult urination, decreased amount of urine).

Tell your doctor if you notice any of the following side-effects:

• dizziness
• hyperactivity
• headache
• nervousness
• lack of or trouble sleeping
• confusion
• drowsy or sleepiness
• nausea
• vomiting, diarrhoea, abdominal pain
• irritation or infection of the vagina that may result in itching, burning sensation, pain and/or discharge from the vagina.

Not all side effects reported for LIZORP are included in this leaflet. Should your general health worsen while taking LIZORP, please consult your doctor, pharmacist or other healthcare professional for advice.

Keep all medicines out of the reach and sight of children. Store at or below 30 ºC. Return all unused medicine to your pharmacist. Do not dispose of unused medicine in drains or sewerage systems (e.g. toilets).