Netvody 40 units/100 ml Solution

    Netvody 40 units/100 ml Solution

    S4

    API: Vasopressin | Company: Cipla Medpro

    1. What NETVODY is and what it is used for

    NETVODY contains vasopressin – a polypeptide hormone. It is an 'antidiuretic' which helps to prevent excess loss of water in your urine and narrows some blood vessels in the body.

    NETVODY is indicated to increase blood pressure in adults with vasodilatory shock who continue to have decreased blood pressure despite fluids and catecholamines.

    2. What you need to know before you are given NETVODY

    Do not receive NETVODY

    • if you are allergic (hypersensitive) to vasopressin or any of the other ingredients of NETVODY (listed in section 6).
    • if you are allergic (hypersensitive) to 8-L-arginine vasopressin.

    Warnings and precautions

    Tell your doctor or health care provider before being given NETVODY:

    • if you suffer from any diseases or conditions associated with your blood vessels, especially the blood vessels of your heart.
    • if you suffer from high blood pressure, heart or kidney disease.
    • have ever had an abnormal electrocardiogram (ECG).
    • heart rhythm disorders.
    • your skin may be monitored for the signs of insufficient blood flow (pallor, cold, pain, abnormal sensations).

    Other medicines and NETVODY

    Always tell your health care provider if you are taking any other medicine. (This includes all complementary or traditional medicines).

    • Catecholamines such as - dopamine, norepinephrine (nor adrenaline), and epinephrine (adrenaline) –may result in an additional increase of blood pressure and heart rate, Your doctor may adjust the dosage of NETVODY while monitoring your blood pressure.

    • Nonsteroidal anti-inflammatory drugs (NSAIDs) such as Indomethacin may prolong the effect of NETVODY leading to greater pumping of the blood by the heart and increase in the resistance to blood flow.

    • The ganglionic blocking agent tetra-ethyl ammonium increases the effect of NETVODY by 20 % in healthy individuals - Your doctor may adjust the dosage of NETVODY while monitoring your blood pressure.

    • Antidepressants such as selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants, and other medicines like haloperidol, chlorpropamide, enalapril, methyldopa, pentamidine, vincristine, cyclophosphamide, ifosfamide, felbamate may increase the effects of NETVODY on narrowing blood vessels and increasing blood pressure, as well as controlling urine output. Your doctor may adjust the dosage of NETVODY while monitoring your blood NETVODY.

    • Certain medicines like demeclocycline, lithium, foscarnet, clozapine may decrease the effect of NETVODY; your doctor will monitor the same and adjust the dose of NETVODY accordingly.

    NETVODY with food, drink, and alcohol

    No data available.

    Pregnancy, breastfeeding and fertility

    NETVODY may produce contraction of uterine muscle that could threaten the continuation of pregnancy. If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, please consult your doctor, pharmacist or other health care provider for advice before taking NETVODY.

    3. How to receive NETVODY

    Route of administration - Parenteral Injection

    You will not be expected to give yourself NETVODY. It will be given to you by a person who is qualified to do so.

    If you receive more NETVODY than you should

    Since a health care provider will administer NETVODY, he / she will control the dosage. However, in the event of overdosage your doctor will manage the overdosage.

    If you forget to take NETVODY

    Since a health care provider will administer NETVODY, it is unlikely that the dose will be missed.

    4. Possible side effects

    NETVODY can have side effects.

    Not all side effects reported for NETVODY are included in this leaflet. Should your general health worsen or if you experience any untoward effects while taking NETVODY, please consult your health care provider for advice.

    If any of the following happens, stop taking NETVODY and tell your doctor immediately or go to the casualty department at your nearest hospital:

    Frequency unknown - frequency cannot be estimated from the available data.

    • Decreased platelets, bleeding that is not easily controlled.
    • An irregular – increase or decrease in heartbeat, Fainting or nearly fainting, have difficulty breathing, chest pain, feeling dizzy or weak, fatigue & tire easily with activity. (Atrial fibrillation, bradycardia).
    • Increased bilirubin levels (if you notice yellow discoloration of eyes or skin, or dark-coloured urine).
    • Decreased urinary output, swelling due to fluid retention, nausea, fatigue and shortness of breath (Acute renal insufficiency).
    • Nausea, headache, confusion and fatigue (Hyponatremia).
    • Ischemic skin lesion (that occur when there is reduced blood to the skin).
    • Diabetes insipidus (a rare disorder that causes the body to make too much urine).

    If you notice any side effects not mentioned in this leaflet, please inform your doctor or pharmacist.

    Reporting of side effects

    If you get side effects, talk to your doctor or, pharmacist. You can also report side effects to SAHPRA via the via the Med Safety APP (Medsafety X SAHPRA) and eReporting platform (who-umc.org) found on the SAHPRA website, or to Cipla Medpro (Pty) Ltd. by e-mail: [email protected] or telephone: 080 222 6662 (toll free). By reporting side effects, you can help provide more information on the safety of NETVODY.

    5. How to store NETVODY

    Ideal Storage: Store between 2 °C and 8 °C (36 °F and 46 °F). Do not freeze.

    Shelf life of the product is 24 months when stored at 2 to 8°C from the date of manufacturing.

    Vials may be held up to 6 months upon removal from refrigeration to room temperature storage conditions (20 °C to 25 °C [68 °F to 77 °F], USP – United States Pharmacopeia Controlled Room Temperature), anytime within the labelled shelf life. Once removed from refrigeration, unopened vial should be marked to indicate the revised 6-months expiration date. If the manufacturer’s original expiration date is shorter than the revised expiration date, then the shorter date must be used. Do not use NETVODY, beyond the manufacturer’s expiration date stamped on the vial.

    The storage conditions and expiration periods are summarized in the following table.

    PackUnopened Refrigerated 2°C to 8°C (36°F to 46°F)Unopened Room Temperature 20°C to 25°C (68°F to 77°F)Do not store above 25°C (77°F)Opened (After First Puncture)
    100 mL VialUntil manufacturer expiration date6 months or until manufacturer expiration date, whichever is earlierNot applicableDo not use after the expiry date stated on the packaging.
    Important Disclaimer

    The Netvody 40 units/100 ml Solution professional information leaflet below is the property of Cipla Medpro and is provided on Somayeza exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Somayeza serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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