Medically reviewed by Bandela Mgoqi (B.Pharm, M.Pharm, MPS). Last updated on September 17, 2026.
What Uralyt ® -U is: substances dissolving urinary aggregates.
What Uralyt ® -U is used for: Uralyt ® -U alkalinises the urine and it is used to:
Do not take/use Uralyt ® -U :
Take special care with Uralyt®-U: Please consult your doctor, pharmacist or other healthcare professional for advice:
Always tell your healthcare provider if you are taking any other medicine (this includes complementary or traditional medicines). Tell your doctor if you are taking any of the following medicines:
Uralyt ® -U should be used with caution during pregnancy and whilst breastfeeding. If you are pregnant or breastfeeding your baby, please consult your doctor, pharmacist or other healthcare professional for advice before taking Uralyt ® -U.
Uralyt ® -U has no or negligible influence on the ability to drive and use machines.
Do not share medicines prescribed for you with any other person. Always take/use Uralyt ® -U exactly as described in this leaflet or as your doctor or pharmacist or nurse has told you. Check with your doctor or pharmacist or nurse if you are not sure. The dosage as determined by your healthcare professional should not be changed. Please adhere to the directions for use, otherwise Uralyt ® -U will not function optimally. To ensure success, it is essential to follow the instructions carefully. Best results can only be obtained by close co-operation.
The usual dose is: The granules should be dissolved by stirring in half a glass of water or fruit juice and taken, preferably, after meals. Unused solution must be discarded.
The treatment is divided into two stages:
Measure the pH of the urine with the indicator paper. Enter the pH value (colour number) on the enclosed test chart. Take the corresponding dose (number of measuring spoonfuls of Uralyt ® -U) and enter it on the chart. Check the pH value of the urine before each dose of Uralyt ® -U. This pH value (5,6; 5,9; 6,2; 6,5; 6,8; 7,0; 7,2; 7,4; 7,7; 8,0) shows the response from the previous dose of Uralyt ® -U. The morning test shows the response from the previous evening dose, the midday test shows the response from the morning dose, etc.
How much and how often should you take Uralyt ® -U? The enclosed measuring spoon holds approximately 2,5 g of the granules. For most patients it has proved satisfactory to take an average daily dose of 4 measures of the granules (10 g Uralyt ® -U) spread uniformly throughout the day in accordance with the following schedule:
| Time | Number of spoonfuls |
|---|---|
| as early as possible (7-8 a.m.) | 1 |
| 2-3 p.m. | 1 |
| as late as possible (about 10 p.m.) | 2 |
This is the standard dosage to stabilise the urine pH within the desired range (6,2 to 6,8) and is the range required for treatment of Uric Acid Calculi . During treatment with uricosuric agents, the pH is stabilised between 6,2 and 6,8 . During cytostatic therapy the urine pH should be at least 7,0 . The dose should be individually adjusted in accordance with the pH recorded. It should however be noted that any necessary correction of the dose occurs on the following day. Examples: If at midday the pH value is found to be too high (7,0 or more) there is no point in immediately cutting down the next dose. A test result of “7,0 or more” at midday means that the morning dose was too high. The right course is to reduce the next morning dose so that the pH response at next midday will then fall within the correct range. The same applies to other recordings. If the morning pH is found to be too low (e.g. 5,9), this means that too small a dose of the granules was taken on the previous evening. Therefore, the next evening dose should be increased. When changing the dose, it is advisable to increase or decrease it in steps of half a spoonful only.
The pH of fluid is a measure of its acidity or alkalinity. For example, pH 7,0 means that the fluid is neither acid nor alkaline – in other words, neutral. pH readings above 7,0 mean that the reaction is increasingly alkaline, while pH values below 7,0 mean increasing acidity. pH values are measured directly by colour changes on the prepared paper strips (indicator papers).
The special indicator paper (enclosed) consists of 52 perforated yellow paper strips and a colour scale with pH numbers. Every morning, at midday and in the evening, before taking Uralyt ® -U, tear off one paper strip and dip it into fresh urine for a few seconds. Alternatively, it may be held in the urine stream. Match the change in colour of the strip at once with the colour scale and mark the corresponding colour number by placing a cross in the appropriate space on the test chart (morning, midday, evening). Then enter the dose of the granules by writing the number of measuring spoonsful in the space directly after the time. When the dose has been correctly adjusted, the test which is carried out three times a day before each dose, will give colour numbers of 6,2; 6,5 or 6,8. If the colour number is over 7,0, reduce the dose, except during cytostatic therapy, when the urine pH should be at least 7,0. Conversely, underdosage is indicated by colour numbers less than 6,2 (5,6 or 5,9). In this case, the dosage must be increased.
Uralyt ® -U can have side effects. In patients with impaired renal function, exceeding the recommended dose may lead to a condition called metabolic alkalosis. The 24-hour fluid intake should be at least 2 to 2½ litres. For heart patients, a lower fluid intake may be necessary.
Not all side effects reported for Uralyt ® -U are included in this leaflet. Should your general health worsen or if you experience any untoward effects while taking Uralyt ® -U , please consult your healthcare professional for advice.
If any of the following happens, stop taking Uralyt ® -U and tell your doctor immediately or go to the casualty department at your nearest hospital:
These are all very serious side effects. If you have them, you may have had a serious allergic reaction to Uralyt ® -U. You may need urgent medical attention or hospitalisation.
Tell your doctor if you notice any of the following: The following side effects have been reported frequently:
The following side effects have been reported less frequently:
If you notice any side effects not mentioned in this leaflet, please inform your doctor or pharmacist.
Reporting of side effects Reporting suspected adverse reactions after authorisation of the medicine is important. It allows continued monitoring of the benefit/risk balance of the medicine. Healthcare providers are asked to report any suspected adverse reactions to SAHPRA via the “6.04 Adverse Drug Reactions Reporting Form”, found online under SAHPRA’s publications: https://www.sahpra.org.za/Publications/Index/8. By reporting side effects, you can help provide more information on the safety of Uralyt ® -U.
• Store all medicines out of reach of children.
• Store at or below 25 ° C.
• Keep container tightly closed.
• Do not use this medicine after the expiry date printed on the container.
• Do not share medicines prescribed for you with others.
• Store in the original package/container.
• Do not store in a bathroom.
• Return all unused medicine to your pharmacist.
• Do not dispose of unused medicine in drains or sewerage systems (e.g. toilets).
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