Medically reviewed by Bandela Mgoqi (B.Pharm, M.Pharm, MPS). Last updated on September 17, 2026.
· Xofluza is used for treatment of influenza (flu) 12 years of age or older, who have experienced flu symptoms for no more than 48 hours and/or you are at high risk of developing influenza complications.
· Xofluza is used to prevent influenza in individuals aged 12 years and older who have been in close contact with someone who is known or suspected to have influenza.
You should not take Xofluza:
Take special care with Xofluza
Talk to your healthcare provider before you receive a live flu vaccine after you have taken Xofluza as no interaction studies with flu vaccines have been performed.
Do not take Xofluza if you are less than 12 years of age or weigh less than 40kg.
Always tell your healthcare professional if you are taking any other medicine. (This includes complementary or traditional medicines).
Do not share medicines prescribed for you with any other person. Always take Xofluza exactly as your doctor has instructed you. You should check with your doctor if you are unsure. Your doctor will prescribe one dose of Xofluza and will tell you how many tablets to take depending on your weight. You can take Xofluza with or without food. Your doctor will tell you how long your treatment with Xofluza will last. If you have the impression that the effect of Xofluza is too strong or too weak, tell your doctor or pharmacist.
If you take more Xofluza than you should:
In the event of overdosage, consult your doctor or pharmacist. If neither is available, contact the nearest hospital or poison control centre.
If you forget to take Xofluza:
As Xofluza is taken as a single dose, take the dose as soon as you remember. If it is more than 48 hours after you showed flu symptoms, contact your doctor for advice.
If you stop taking Xofluza:
Xofluza is given as a single dose therefore no effects after stopping taking Xofluza are expected.
Xofluza can have side effects
Not all side effects reported for Xofluza are included in this leaflet. Should your general health worsen or if you experience any untoward effects while taking Xofluza, please consult your doctor, pharmacist or healthcare professional for advice. The most frequent side effects of Xofluza include:
If you notice any side effects not mentioned in this leaflet, please inform your doctor or pharmacist.
Reporting of side effects
Reporting suspected adverse reactions after authorisation of the medicine is important. It allows continued monitoring of the benefit/risk balance of the medicine. Healthcare professionals are asked to report any suspected adverse reactions to SAHPRA via the “6.04 Adverse Drug Reaction Report Form”, found online under SAHPRA’s publications: https://www.sahpra.org.za/Publications/Index/8
Store tablets at or below 30 C. Store blister in outer carton until required for use, in order to protect from moisture and light. Store all medicines out of reach of children. Keep blister packs in outer container until required for use. Do not use this medicine after the expiry date (EXP) stated on the outer carton.
Disposal of unused/expired medicine : The release of pharmaceuticals in the environment should be minimised. Medicines should not be disposed of via wastewater and disposal through household waste should be avoided. Use established collection systems, if available in your location.
The Xofluza ® 20 mg Film-Coated Tablets professional information leaflet below is the property of Roche Products and is provided on Somayeza exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Somayeza serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
The patient information text is available above. Load the original PDF only when you need it.