Nurofen Period Pain Ibuprofen 400 mg Tablets

The active ingredient is ibuprofen. Ibuprofen belongs to a group of medicines non-steroidal anti-inflammatory drugs (NSAIDs). These medicines provide relief by changing body's response to pain. NUROFEN PERIOD PAIN is used for relieving period pain.

Do not take NUROFEN if :

• You are allergic to ibuprofen, aspirin (or other similar painkillers known as NSAIDs) or other ingredients of NUROFEN PERIOD PAIN;
• You have suffered from ulcers, shortness of breath, asthma, runny nose or hives after using aspirin or other similar painkillers (NSAIDs);
• You are suffering from heart failure;
• You have severe liver impairment;
• You have severe kidney impairment;
• You have stomach ulcers or bleeding in the gut (or you previously suffered from these);
• Children aged < 12 years old;
• You are in the last trimester of pregnancy.

Take special care with NUROFEN PERIOD PAIN : The following conditions may be aggravated whilst on treatment with NUROFEN PERIOD PAIN, you must consult your doctor if any of the following apply to you before continuing with treatment:

• Problems with bleeding;
• Taking medicines for treating blood clotting conditions (coumarin anticoagulants);
• Heart disease and/or stroke;
• High blood pressure;
• Stomach problems such as bleeding or ulcers in the gut (especially if you are an elderly);
• Asthma or other allergies;
• Using similar painkillers like aspirin (NSAIDs);
• Joint pain skin disorders (systemic lupus erythematosus and mixed connective tissue disease);
• Impaired kidneys;
• Liver impairment.

Treatment with NUROFEN PERIOD PAIN may lead to the following problems. If any of the following happens, discontinue treatment and consult your doctor:

• Drug reaction with eosinophillia and systemic symptoms (DRESS): life-threatening reaction which may resemble a flu-like infection, other signs may include rash, facial swelling, abdominal pain and abnormal heartbeat.
• Severe skin reactions like Stevens-Johnson syndrome and toxic epidermal necrolysis: these are indicated by fever and body aches, painful/reddish rash on the skin, mouth, throat and/or genitals followed by blistering.
• Fertility problems in women: NUROFEN PERIOD PAIN may cause impairment of female fertility but this is reversible upon withdrawal of treatment.
• If you have been taking NUROFEN PERIOD PAIN for a couple of days and your symptoms persist or become worse as you might be suffering from an underlying infection that cannot be treated by NUROFEN PERIOD PAIN. Your doctor will need to assess you in order to administer proper treatment for your condition.

Do not share medicines prescribed for you with any other person. Always take NUROFEN PERIOD PAIN exactly as described in this leaflet or as your doctor, pharmacist or nurse has told you. Check with your doctor, pharmacist or nurse if you are not sure. The usual dose is one(1) tablet three (3) times a day. Do not exceed 3 tablets in any 24 hours. Tablets must be taken with water. Do not give NUROFEN PERIOD PAIN to children under 12 years. If symptoms persist for more than 7 days or worsen or new symptoms occur, consult your doctor. Use the lowest effective dose for the shortest possible duration of treatment. If you take more NUROFEN PERIOD PAIN than you should: In the event of overdosage, consult your doctor or pharmacist. If neither is available, contact the nearest hospital or poison centre. The following signs may occur: nausea, vomiting, stomach pain, headache, dizziness, drowsiness, involuntary eye movement, blurred vision, ringing in the ear. Rare symptoms include low blood pressure (you may experience light-headedness) and loss of consciousness. If you forget to take NUROFEN PERIOD PAIN: Do not take a double dose to make up for forgotten individual doses.

NUROFEN PERIOD PAIN can have side effects. Not all side effects reported for NUROFEN PERIOD PAIN are included in this leaflet. Should your general health worsen or if you experience any untoward effects while taking NUROFEN PERIOD PAIN, please consult your health care provider for advice. If any of the following happens, stop taking NUROFEN PERIOD PAIN and tell your doctor immediately or go to the casualty department at your nearest hospital:

• Anaphylaxis, indicated by swelling of mouth, throat and face or limbs, and inability to breathe.
• Asthma or worsening of your asthma.
• Allergic reactions such as rash, hives, itchy skin.
• DRESS syndrome: life-threatening reaction which may resemble a flu-like infection, other signs may include rash, facial swelling, abdominal pain and abnormal heartbeat.
• Severe skin reactions like Stevens-Johnson syndrome and toxic epidermal necrolysis: these are indicated by fever and body aches, painful/reddish rash on the skin, mouth, throat and/or genitals followed by blistering.
• Severe low blood pressure (can be indicated by fainting or loss of consciousness).

These are all very serious side effects. If you have them, you may have had a serious reaction to NUROFEN PERIOD PAIN. You may need urgent medical attention or hospitalisation. Tell your doctor immediately or go to the casualty department at your nearest hospital if you notice any of the following:

Less frequent side effects :

• Blood disorders, this can make you prone to opportunistic illnesses, bruising easily and being prone to bleeding. First signs are fever, sore throat, superficial mouth ulcers, flu-like symptoms, severe exhaustion, unexplained bleeding and bruising.
• Aseptic meningitis (inflammation of the brain): signs include stiff neck, headache, nausea, vomiting, fever or disorientation.
• High blood pressure
• Vomiting blood
• Painful ulcers in the stomach and mouth
• Bleeding in the gut
• Liver disease (may be indicated by tummy pain and yellowing of the eyes and skin)

Side effects with unknown frequencies:

• Heart disease: may be indicated by chest pain, fatigue, leg swelling and/or shortness of breath.
• Kidney disease: signs may include reduced urine output, nausea and swelling of feet/legs and ankles

These are all serious side effects. You may need urgent medical attention. Tell your doctor if you notice any of the following:

Less frequent side effects:

• Skin rash
• Abdominal pain, nausea, diarrhoea (runny tummy), flatulence, indigestion, constipation, vomiting, black or tarry stools.

Side effects with unknown frequencies:

• Photosensitivity reactions.

If you notice any side effects not mentioned in this leaflet, please inform your doctor or pharmacist.

Reporting of side effects: If you get side effects, talk to your doctor, pharmacist or nurse. You can also report side effects to SAHPRA via the “6.04 Adverse Drug Reaction Reporting Form”, found online under SAHPRA’s publications: https://www.sahpra.org.za/Publications/Index/8. By reporting side effects, you can help provide more information on the safety of NUROFEN PERIOD PAIN.

Store at or below 25 ºC. KEEP OUT OF REACH OF CHILDREN.